Wednesday, December 25, 2013

Kidney Tubular Cells Generated from Stem Cells

Researchers have successfully coaxed stem cells to become kidney tubular cells, a significant advance toward one day using regenerative medicine, rather than dialysis and transplantation, to treat kidney failure. The findings are published in the Journal of the American Society of Nephrology (JASN).

Chronic kidney disease is a major global public health problem, and when patients progress to kidney failure, their treatment options are limited to dialysis and kidney transplantation. Regenerative medicine—which involves rebuilding or repairing tissues and organs—may offer a promising alternative.

Albert Lam, MD, Benjamin Freedman, PhD, Ryuji Morizane, MD, PhD (Brigham and Women’s Hospital), and their colleagues have been working for the past five years to develop strategies to coax human pluripotent stem cells—particularly human embryonic stem (ES) cells and human induced pluripotent stem (iPS) cell—into kidney cells for the purposes of kidney regeneration.

Read complete article
Subscribe to NBIC News